Kiran Bharat Lokhande Selected Research

Resveratrol

12/2023	Exploring binding mode assessment of novel kaempferol, resveratrol, and quercetin derivatives with PPAR-α as potent drug candidates against cancer.
10/2023	Dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) by resveratrol derivatives in cancer therapy: in silico approach.
1/2022	Probing intermolecular interactions and binding stability of kaempferol, quercetin and resveratrol derivatives with PPAR-γ: docking, molecular dynamics and MM/GBSA approach to reveal potent PPAR- γ agonist against cancer.
8/2020	Exploring conformational changes of PPAR-Ɣ complexed with novel kaempferol, quercetin, and resveratrol derivatives to understand binding mode assessment: a small-molecule checkmate to cancer therapy.

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Kiran Bharat Lokhande Research Topics

Disease

15	Neoplasms (Cancer) 01/2024 - 01/2018
6	COVID-19 10/2023 - 01/2020
3	Neoplasm Metastasis (Metastasis) 10/2023 - 01/2023
2	Carcinogenesis 01/2024 - 01/2023
2	Visceral Leishmaniasis (Kala Azar) 12/2023 - 01/2022
2	Inflammation (Inflammations) 10/2023 - 01/2023
2	Mouth Neoplasms (Oral Cancer) 09/2023 - 10/2021
2	Breast Neoplasms (Breast Cancer) 03/2023 - 01/2023
2	Infections 01/2023 - 12/2021
1	Lung Neoplasms (Lung Cancer) 10/2023
1	Triple Negative Breast Neoplasms 06/2023
1	Mpox (monkeypox) 01/2023
1	Pneumonia (Pneumonitis) 01/2022
1	Severe Acute Respiratory Syndrome 01/2022
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018
1	Myocardial Infarction 07/2017

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 01/2024 - 01/2018
4	ResveratrolIBA 12/2023 - 08/2020
4	QuercetinIBA 12/2023 - 08/2020
4	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 12/2023 - 08/2020
3	VaccinesIBA 12/2023 - 01/2022
3	kaempferolIBA 12/2023 - 08/2020
3	LigandsIBA 12/2023 - 11/2019
3	AcidsIBA 09/2023 - 01/2023
3	Antiviral Agents (Antivirals)IBA 01/2022 - 12/2021
2	EpitopesIBA 12/2023 - 01/2022
2	Peptides (Polypeptides)IBA 12/2023 - 01/2022
2	Transcription Factors (Transcription Factor)IBA 12/2023 - 08/2020
2	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 03/2023 - 01/2023
2	flavanoneIBA 03/2023 - 01/2023
2	deguelinIBA 08/2022 - 11/2019
2	Cyclin D1IBA 08/2022 - 11/2019
2	Cyclin EIBA 08/2022 - 11/2019
1	FlavonesIBA 01/2024
1	FlavonoidsIBA 01/2024
1	Niacin (Nicotinic Acid)FDA LinkGeneric 10/2023
1	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 10/2023
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 10/2023
1	ThiosemicarbazonesIBA 10/2023
1	HydrazonesIBA 10/2023
1	Isonicotinic Acids (Isonicotinic Acid)IBA 10/2023
1	Tumor Suppressor Protein p53IBA 06/2023
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 06/2023
1	PhytochemicalsIBA 06/2023
1	Nonesterified Fatty Acids (NEFA)IBA 03/2023
1	erucic acidIBA 03/2023
1	nervonic acidIBA 03/2023
1	CyclinsIBA 03/2023
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 03/2023
1	Cyclin DIBA 03/2023
1	raf KinasesIBA 01/2023
1	Ellagic AcidIBA 01/2023
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2023
1	dTMP kinaseIBA 01/2023
1	DNA Ligases (Ligases, DNA)IBA 01/2023
1	Cysteine Proteases (Cysteine Protease)IBA 01/2023
1	InflammasomesIBA 01/2023
1	Aurora Kinase AIBA 01/2023
1	remdesivirIBA 01/2022
1	Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA 01/2022
1	HLA-A*02:01 antigenIBA 01/2022
1	Vitamin D FDA LinkGeneric 01/2022
1	N- 3- (3- (3- methoxy- 4- oxazol- 5- ylphenyl)ureido)benzylcarbamic acid tetrahydrofuran-3-yl esterIBA 12/2021
1	AZ3451IBA 12/2021
1	Carrier Proteins (Binding Protein)IBA 12/2021
1	silmitasertibIBA 12/2021
1	Mitoxantrone (Novantrone)FDA LinkGeneric 11/2021
1	Leucovorin (Folinic Acid)FDA Link 11/2021
1	birinapantIBA 11/2021
1	N'- (3,4- dihydroxybenzylidene)- 3- hydroxy- 2- naphthahydrazideIBA 11/2021
1	Pyruvate KinaseIBA 10/2021
1	Glucose (Dextrose)FDA LinkGeneric 10/2021
1	SAICARIBA 10/2021
1	Biomarkers (Surrogate Marker)IBA 10/2021
1	EnzymesIBA 10/2021
1	Culture MediaIBA 01/2021
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 08/2020
1	Linoleic Acid (Linoleate)IBA 08/2020
1	CarbohydratesIBA 01/2020
1	Phosphotransferases (Kinase)IBA 01/2018
1	Gefitinib (Iressa)FDA Link 01/2018
1	Growth Factor ReceptorsIBA 01/2018
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 07/2017

Therapy/Procedure

5	Therapeutics 10/2023 - 01/2018
1	Drug Therapy (Chemotherapy) 01/2022